产品货号：
Z36116
中文名称：
PKC Epsilon/PRKCE抗体
英文名称：
Anti-PKC Epsilon/PRKCE Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-PKC Epsilon/PRKCE Antibody |
| 指标别名 | PKC epsilon;PKCE;PRKCE;Protein kinase C epsilon type;protein kinase C;epsilon |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,ICC/IF,FCM |
| 基因名称 | PRKCE |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthesized peptide derived from human PKC epsilon This is calcium-independent,phospholipid-dependent,serine- and threonine-specific enzyme.PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins.PKC also serves as the receptor for phorbol esters,a class of tumor promoters. |
| 实际分子量 | 88KD |
| 成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
| 纯化方式 | Affinity-chromatography |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Protein kinase C epsilon type,also known as PKCE,is an enzyme that in humans is encoded by the PRKCE gene.The protein encoded by this gene is one of the PKC family members.PRKCE is mapped to 2p21.This kinase has been shown to be involved in many different cellular functions,such as apoptosis,cardioprotection from ischemia,heat shock response,as well as insulin exocytosis.It has been found that activation of PRKCE can induce VR1 channel activity at room temperature in the absence of any other agonist.PRKCE gene plays a role in apoptosis signaling pathways in thyroid cells and it has been indicated that a naturally occurring PRKCE mutant that functions as a dominant negative can block cell death triggered by a variety of stimuli.Expression of PRKCE inhibits chemotherapy-induced caspase-3 activation and apoptosis,thereby leading to cell survival. |
| Uniprot ID | Q02156 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:20～100ICC/IF 1:50～1:200 FC 1:50 |
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